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Dental school · D1 Head & Neck Anatomy · Review sheet · Free

Lymph Drainage & Fascial Spaces

Chapter: Fascial Spaces & Spread of Odontogenic Infection

Updated 2026-10-20

Where dental structures drain (primary nodes)

NodesDrain
SubmentalMandibular incisors and their gingiva, tip of the tongue, floor of mouth anteriorly, chin, middle of the lower lip
SubmandibularMost other teeth and gingiva, cheeks, upper lip, lateral lower lip, anterior hard palate, body of the tongue; also receive submental drainage
Superior deep cervical (incl. jugulodigastric)Maxillary third molars (often), posterior hard palate, soft palate, base of the tongue, tonsils
  • All head and neck lymph ends in the deep cervical chain and then the thoracic duct (left) or right lymphatic duct.
  • Infected nodes: tender, soft, mobile. Malignant nodes: hard, painless, fixed (matted).

Spread of odontogenic infection

SourceRuleSpace
Mandibular incisorsApex below the mentalis attachmentSubmental
Mandibular premolars and first molarApex above the mylohyoid lineSublingual
Mandibular second and third molarsApex below the mylohyoid lineSubmandibular
Mandibular molars (buccal)Apex below the buccinator attachmentBuccal space (above it: vestibular abscess)
Maxillary molars (buccal)Apex above the buccinator attachmentBuccal space (below it: vestibular abscess)
Maxillary canineApex above the levator anguli orisCanine (infraorbital) space; danger of cavernous sinus spread
Maxillary third molarPosterior and superior spreadInfratemporal space
Mandibular third molarPosterior spreadMasticator spaces (pterygomandibular, submasseteric) → trismus; then lateral pharyngeal

Danger pathways

  • Ludwig angina: bilateral cellulitis of the submandibular, sublingual and submental spaces, usually from mandibular molars; raised tongue, drooling, brawny neck swelling, airway compromise. Airway first, then drainage and antibiotics.
  • Lateral pharyngeal → retropharyngeal → danger space (between the alar and prevertebral fascia) → posterior mediastinum.
  • The pterygomandibular space is where the IANB is deposited; a contaminated needle can seed infection there.

⚠️ Common traps

  • Sending second and third molar infections to the sublingual space: their apices are below the mylohyoid line, so they go submandibular.
  • Draining the mandibular incisors to the submandibular nodes: they drain to the submental nodes first.
  • Treating Ludwig angina as a simple abscess: it is a spreading cellulitis and an airway emergency.
  • Calling a hard, fixed, painless node 'reactive'.

Mini-quiz

Pick an answer to see right away whether it is correct and why.

  1. A periapical abscess on a mandibular second molar perforates the lingual plate. Which space is most likely involved?
  2. Primary lymph drainage of the mandibular central incisors is to the:
  3. Which tooth's infection carries the greatest risk of spreading to the cavernous sinus through the canine space?
  4. Ludwig angina involves which spaces?
  5. A palpable node is hard, painless and fixed. This is most suggestive of:
0 of 5 answered

Answer key: 1 A · 2 B · 3 C · 4 B · 5 C